The Imipenem – 10 μg Antibiotic Disc – Bioanalyse is a paper disc impregnated with 10 micrograms of imipenem, a carbapenem antibiotic. It is used in the disc diffusion method of antimicrobial susceptibility testing to determine the susceptibility of bacteria to imipenem.

The disc diffusion method is a simple and inexpensive method for testing the susceptibility of bacteria to antibiotics. It is based on the principle that bacteria that are susceptible to an antibiotic will not be able to grow near the disc containing the antibiotic.

To perform the disc diffusion test, a bacterial suspension is spread on the surface of an agar plate. Antibiotic discs are then placed on the surface of the agar plate. The plates are incubated for 16-24 hours, and then the zones of inhibition around the discs are measured. The size of the zone of inhibition is proportional to the susceptibility of the bacteria to the antibiotic.

The Imipenem – 10 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis and treatment of a wide range of serious bacterial infections, including:

• Sepsis
• Meningitis
• Pneumonia
• Intra-abdominal infections
• Urinary tract infections
• Skin and soft tissue infections

Imipenem is a broad-spectrum antibiotic, meaning that it is effective against a wide range of bacteria, including both Gram-positive and Gram-negative bacteria. It is also effective against some bacteria that are resistant to other antibiotics.

Interpretation of results:

| Zone of inhibition | Interpretation | |—|—|—| | ≥ 20 mm | Susceptible | | 16-19 mm | Intermediate | | < 16 mm | Resistant |

It is important to note that the disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.

The Imipenem – 10 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis and treatment of a wide range of serious bacterial infections. However, it is important to be aware of the potential side effects of imipenem before using it. Imipenem can cause side effects such as nausea, vomiting, diarrhea, and rash. In rare cases, imipenem can cause serious side effects such as seizures and allergic reactions.

Limitations of the Imipenem – 10 μg Antibiotic Disc – Bioanalyse:

• The disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.
• The disc diffusion method is not able to detect all bacteria that are resistant to imipenem. For example, some strains of Pseudomonas aeruginosa are resistant to imipenem, but they may not produce a zone of inhibition around an imipenem disc.
• The disc diffusion method can be affected by the type of agar plate used, the incubation temperature, and the inoculum density. Therefore, it is important to follow standardized procedures when performing the disc diffusion test.

Additional information about imipenem:

Imipenem is a carbapenem antibiotic. Carbapenems are a class of broad-spectrum antibiotics that are reserved for the treatment of serious bacterial infections. Imipenem is a bactericidal antibiotic, which means that it kills bacteria.

Imipenem is a safe and effective antibiotic for most people. However, it is important to be aware of the potential side effects of imipenem before using it. Imipenem is not recommended for people who are allergic to carbapenem antibiotics or for people with kidney problems.

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