Azithromycin – 15 μg Antibiotic Disc – Bioanalyse

Azithromycin – 15 μg Antibiotic Disc – Bioanalyse is a paper disc impregnated with 15 micrograms of azithromycin, an azalide antibiotic. It is used in the disc diffusion method of antimicrobial susceptibility testing to determine the susceptibility of bacteria to azithromycin.

The disc diffusion method is a simple and inexpensive method for testing the susceptibility of bacteria to antibiotics. It is based on the principle that bacteria that are susceptible to an antibiotic will not be able to grow near the disc containing the antibiotic.

To perform the disc diffusion test, a bacterial suspension is spread on the surface of an agar plate. Antibiotic discs are then placed on the surface of the agar plate. The plates are incubated for 16-24 hours, and then the zones of inhibition around the discs are measured. The size of the zone of inhibition is proportional to the susceptibility of the bacteria to the antibiotic.

The Azithromycin – 15 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis and treatment of bacterial infections. It can be used to identify bacteria that are susceptible to azithromycin, and to determine the optimal dose of azithromycin to use for treatment.

Interpretation of results:

• Susceptible: Zone of inhibition is greater than or equal to 23 millimeters.
• Intermediate: Zone of inhibition is 17-22 millimeters.
• Resistant: Zone of inhibition is less than 17 millimeters.

It is important to note that the disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.

The Azithromycin – 15 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis and treatment of a wide range of bacterial infections, including:

• Community-acquired pneumonia
• Acute bacterial sinusitis
• Acute otitis media
• Pharyngitis/tonsillitis
• Skin and soft tissue infections
• Lyme disease
• Mycoplasma pneumoniae infections
• Chlamydia pneumoniae infections
• Legionella pneumophila infections

Limitations of the Azithromycin – 15 μg Antibiotic Disc – Bioanalyse:

• The disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.
• The disc diffusion method is not able to detect all bacteria that are resistant to azithromycin. For example, some strains of Streptococcus pneumoniae and Streptococcus pyogenes are resistant to azithromycin, but they may not produce a zone of inhibition around an azithromycin disc.
• The disc diffusion method can be affected by the type of agar plate used, the incubation temperature, and the inoculum density. Therefore, it is important to follow standardized procedures when performing the disc diffusion test.

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