Mecillinam – 10 μg Antibiotic Disc – Bioanalyse

Mecillinam – 10 μg Antibiotic Disc – Bioanalyse is a paper disc impregnated with 10 micrograms of mecillinam, a penicillinaceous antibiotic. It is used in the disc diffusion method of antimicrobial susceptibility testing to determine the susceptibility of bacteria to mecillinam.

Mecillinam is a narrow-spectrum antibiotic, meaning that it is only effective against a limited range of bacteria. It is primarily used to treat infections caused by Gram-negative bacteria, such as:

• Escherichia coli (E. coli)
• Salmonella
• Shigella

Mecillinam is not effective against Gram-positive bacteria, such as Staphylococcus aureus (S. aureus).

Interpretation of results:

| Zone of inhibition | Interpretation | |—|—|—| | ≥ 15 mm | Susceptible | | 13-14 mm | Intermediate | | < 13 mm | Resistant |

It is important to note that the disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.

The Mecillinam – 10 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis and treatment of a variety of bacterial infections. However, it is important to be aware of the potential side effects of mecillinam before using it. Mecillinam can cause side effects such as nausea, vomiting, diarrhea, and rash. In rare cases, mecillinam can cause serious side effects such as anaphylaxis and Stevens-Johnson syndrome.

Limitations of the Mecillinam – 10 μg Antibiotic Disc – Bioanalyse:

• The disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.
• The disc diffusion method is not able to detect all bacteria that are resistant to mecillinam. For example, some strains of E. coli are resistant to mecillinam, but they may not produce a zone of inhibition around a mecillinam disc.
• The disc diffusion method can be affected by the type of agar plate used, the incubation temperature, and the inoculum density. Therefore, it is important to follow standardized procedures when performing the disc diffusion test.

Additional information about mecillinam:

Mecillinam is a safe and effective antibiotic for most people. However, it is important to be aware of the potential side effects of mecillinam before using it. Mecillinam is not recommended for people who are allergic to penicillins or other beta-lactam antibiotics.

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