Nalidixic Acid – 30 μg Antibiotic Disc – Bioanalyse is a paper disc impregnated with 30 micrograms of nalidixic acid, a quinolone antibiotic. It is used in the disc diffusion method of antimicrobial susceptibility testing to determine the susceptibility of bacteria to nalidixic acid.

Nalidixic acid is a narrow-spectrum antibiotic, meaning that it is only effective against a limited range of bacteria. It is primarily used to treat urinary tract infections caused by Gram-negative bacteria such as Escherichia coli and Salmonella. Nalidixic acid is also used to treat some types of diarrhea caused by bacteria.

Interpretation of results:

| Zone of inhibition | Interpretation | |—|—|—| | ≥ 21 mm | Susceptible | | 16-20 mm | Intermediate | | < 16 mm | Resistant |

It is important to note that the disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.

The Nalidixic Acid – 30 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis and treatment of urinary tract infections and other types of infections caused by Gram-negative bacteria. However, it is important to be aware of the potential side effects of nalidixic acid before using it. Nalidixic acid can cause side effects such as:

• Nausea
• Vomiting
• Diarrhea
• Headache
• Dizziness
• Skin rash

In rare cases, nalidixic acid can cause serious side effects such as:

• Seizures
• Liver problems
• Tendon rupture

Limitations of the Nalidixic Acid – 30 μg Antibiotic Disc – Bioanalyse:

• The disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.
• The disc diffusion method is not able to detect all bacteria that are resistant to nalidixic acid. For example, some strains of Escherichia coli are resistant to nalidixic acid, but they may not produce a zone of inhibition around a nalidixic acid disc.
• The disc diffusion method can be affected by the type of agar plate used, the incubation temperature, and the inoculum density. Therefore, it is important to follow standardized procedures when performing the disc diffusion test.

Additional information about nalidixic acid:

Nalidixic acid is a safe and effective antibiotic for most people. However, it is important to be aware of the potential side effects of nalidixic acid before using it. Nalidixic acid is not recommended for people who are allergic to nalidixic acid or other quinolone antibiotics. Nalidixic acid is also not recommended for children under the age of 12, pregnant women, or breastfeeding women.

Buy Best Biochemistry Analyzer From Medistore