Ofloxacin – 5 μg Antibiotic Disc – Bioanalyse is a paper disc impregnated with 5 micrograms of ofloxacin, a fluoroquinolone antibiotic. It is used in the disc diffusion method of antimicrobial susceptibility testing to determine the susceptibility of bacteria to ofloxacin.

Ofloxacin is a broad-spectrum antibiotic, meaning that it is effective against a wide range of bacteria, including both Gram-positive and Gram-negative bacteria. It is used to treat a variety of infections, including:

• Urinary tract infections
• Respiratory infections
• Skin and soft tissue infections
• Bone and joint infections
• Gastrointestinal infections
• Typhoid fever
• Gonorrhea

Ofloxacin is also used to prevent infections before surgery.

Interpretation of results:

| Zone of inhibition | Interpretation | |—|—|—| | ≥ 21 mm | Susceptible | | 16-20 mm | Intermediate | | < 16 mm | Resistant |

It is important to note that the disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.

The Ofloxacin – 5 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis and treatment of a wide range of bacterial infections. However, it is important to be aware of the potential side effects of ofloxacin before using it. Ofloxacin can cause side effects such as:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Rash

In rare cases, ofloxacin can cause serious side effects such as:

• Seizures
• Tendon rupture
• Liver damage
• Kidney damage

Limitations of the Ofloxacin – 5 μg Antibiotic Disc – Bioanalyse:

• The disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.
• The disc diffusion method is not able to detect all bacteria that are resistant to ofloxacin. For example, some strains of Pseudomonas aeruginosa are resistant to ofloxacin, but they may not produce a zone of inhibition around a ofloxacin disc.
• The disc diffusion method can be affected by the type of agar plate used, the incubation temperature, and the inoculum density. Therefore, it is important to follow standardized procedures when performing the disc diffusion test.

Additional information about ofloxacin:

Ofloxacin is a safe and effective antibiotic for most people when used as directed. However, it is important to be aware of the potential side effects of ofloxacin before using it. Ofloxacin is not recommended for people who are allergic to ofloxacin or other fluoroquinolone antibiotics. Ofloxacin is also not recommended for children under the age of 18, pregnant women, or breastfeeding women.

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