Piperacillin – 100 μg Antibiotic Disc – Bioanalyse is a paper disc impregnated with 100 micrograms of piperacillin, a beta-lactam antibiotic. It is used in the disc diffusion method of antimicrobial susceptibility testing to determine the susceptibility of bacteria to piperacillin.

Piperacillin is a broad-spectrum antibiotic, meaning that it is effective against a wide range of bacteria, including both Gram-positive and Gram-negative bacteria. It is used to treat a variety of infections, including:

• Urinary tract infections
• Respiratory infections
• Skin and soft tissue infections
• Bone and joint infections
• Gastrointestinal infections
• Sepsis
• Meningitis

Piperacillin is also used to prevent infections before surgery.

Interpretation of results:

| Zone of inhibition | Interpretation | |—|—|—| | ≥ 17 mm | Susceptible | | 13-16 mm | Intermediate | | < 13 mm | Resistant |

It is important to note that the disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.

The Piperacillin – 100 μg Antibiotic Disc – Bioanalyse is a valuable tool for the diagnosis and treatment of a wide range of bacterial infections. However, it is important to be aware of the potential side effects of piperacillin before using it. Piperacillin can cause side effects such as:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Rash

In rare cases, piperacillin can cause serious side effects such as:

• Seizures
• Allergic reactions, including anaphylaxis
• Liver damage
• Kidney damage

Limitations of the Piperacillin – 100 μg Antibiotic Disc – Bioanalyse:

• The disc diffusion method is only a semi-quantitative method for testing the susceptibility of bacteria to antibiotics. For more accurate results, other methods such as broth microdilution or agar dilution should be used.
• The disc diffusion method is not able to detect all bacteria that are resistant to piperacillin. For example, some strains of Pseudomonas aeruginosa are resistant to piperacillin, but they may not produce a zone of inhibition around a piperacillin disc.
• The disc diffusion method can be affected by the type of agar plate used, the incubation temperature, and the inoculum density. Therefore, it is important to follow standardized procedures when performing the disc diffusion test.

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